Altered Wnt signalling in intervertebral disc degeneration
نویسندگان
چکیده
منابع مشابه
Inflammatory mediators and signalling pathways controlling intervertebral disc degeneration.
Intervertebral disc (IVD) degeneration (IDD) is one of the major causes of back pain, a condition that represents a serious socio-economic burden. Deeper knowledge of the complex and fine relationship between IVD degeneration, tissue inflammation and pain, appears to be critical to improve the current therapies, which have so far proven themselves ineffective. Upon degeneration, IVD tissues bec...
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Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a problem with a heavy economic burden, which has been increasing in prevalence as populations age. Deeper knowledge of the complex spatial and temporal orchestration of cellular interactions and extracellular matrix remodelling is critical to improve current IVD therapies, which have so far proved unsatisfactor...
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ژورنال
عنوان ژورنال: Nature Reviews Rheumatology
سال: 2013
ISSN: 1759-4790,1759-4804
DOI: 10.1038/nrrheum.2013.22